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Research Articles

Evaluation of demarcation line in collagen cross linking and it’s effect on K value stability in keratoconus

Authors:

D.S. Wijesundere ,

Postgraduate Trainee in Ophthalmology, Sri Jayawardenepura General Hospital, Kotte, LK
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W.V.N. Nadeeshani,

Registrar in Ophthalmology, Sri Jayawardenepura General Hospital, Kotte, LK
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L.P. Hettige,

Senior Registrar in Ophthalmology, Sri Jayawardenepura General Hospital, Kotte, LK
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D.H.H. Wariyapola

Consultant Ophthalmologist, Sri Jayawardenepura General Hospital, Kotte, LK
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Abstract

Introduction: Keratoconus is a progressive corneal ectatic disorder where collagen cross linking is used to prevent disease progression. The demarcation line is the transition zone between cross linked and untreated portions of the cornea.

 

Objective: To assess the relationship between the presence of a demarcation line and the stability of K values in patients who have undergone collagen cross-linking (CXL).

 

Method: A cohort study was conducted on 30 patients undergoing CXL for keratoconus between the period 2017 June to 2018 June. The patients were reviewed at one month, 6 months, and 1 year post operatively and the nature and depth of the demarcation line were assessed. Pre procedure Kmax and post procedure Kmax values were calculated.

 

Results: There was no statistically significant change in Kmax at 1 month, 6 months and 1 year after cross linking compared to pre op value. Therefore, a stable Kmax value was achieved after CXL.

 

Discussion & Conclusion: The presence and depth of the demarcation line which is a transition zone between the cross linked and untreated portions of the cornea is believed to indicate the effectiveness of the CXL procedure. Corneal collagen crosslinking stabilizes K values in patients with keratoconus. The depth and visibility of the demarcation line seen after cross linking does not have a significant effect on the K value stability.

How to Cite: Wijesundere DS, Nadeeshani WVN, Hettige LP, Wariyapola DHH. Evaluation of demarcation line in collagen cross linking and it’s effect on K value stability in keratoconus. Journal of the College of Ophthalmologists of Sri Lanka. 2020;26(1):11–4. DOI: http://doi.org/10.4038/jcosl.v26i1.26
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Published on 01 Jun 2020.
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